How Much Do Nurse Practitioners Make in South Carolina?
Median wage from BLS May 2025 — and the after-tax number the salary sites skip. Tax year 2026.
Quick answer
According to payandtaxes.com's analysis of BLS May 2025 data and 2026 tax law, the median Nurse Practitioners in South Carolina earns $123,290 per year and takes home $89,295 ($7,441/month) — a keep-rate of 72.4%, with 5,670 employed in the state.
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| Gross pay | $10,274.17 |
| Federal income tax | $1,526.96 |
| Social Security | $637.00 |
| Medicare | $148.98 |
| South Carolina state income tax | $520.03 |
| You keep | $7,441.21 |
How much do Nurse Practitioners make in South Carolina?
The median Nurse Practitioners in South Carolina earns $123,290 per year (BLS May 2025), about $59.28 per hour.
What is that after taxes?
$123,290 gross in South Carolina keeps $89,295 after federal income tax ($18,323), FICA ($9,432) and state income tax ($6,240) — $7,441 per month, a 72.4% keep-rate.
How does South Carolina compare to the national median for Nurse Practitioners?
The South Carolina median is $9,010 below the national median of $132,300.
Which state pays Nurse Practitioners the most?
California has the highest median gross for Nurse Practitioners at $168,520 — but compare take-home, not gross: state taxes change the order.
Nurse Practitioners salary in every state · South Carolina paycheck calculator · South Carolina minimum wage